How to use 'pandas replace column values' in Python

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39def _drop_col(self, df):
40 '''
41 Drops last column, which was added in the parsing procedure due to a
42 trailing white space for each sample in the text file
43 Arguments:
44 df: pandas dataframe
45 Return:
46 df: original df with last column dropped
47 '''
48 return df.drop(df.columns[-1], axis=1)
78def _clean_column(self, column):
79 if not isinstance(column, (int, str, unicode)):
80 raise ValueError('{} is not a valid column'.format(column))
81 return column in self.df.columns

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